Susan M. Manzi, M.D., M.P.H.

Titles:
·Associate Professor of Medicine,
 Division of Rheumatology and Clinical Immunology
·Director of Clinical Research Program in Systemic Lupus Erythematosus

Address:

BST South 722      3500 Terrace Street      University of Pittsburgh      Pittsburgh, PA 15261

Office Telephone: (412) 383-8734
Office Fax: (412) 383-8753

Degrees:
·B.S., University of Notre Dame
·M.D., University of Pittsburgh
·M.P.H., Graduate School of Public Health, University of Pittsburgh

Postgraduate Training:
·Internship and Residency in Internal Medicine, Duke University Medical Center
·Postdoctoral Fellowship, Rheumatology, Duke University Medical Center
·Postdoctoral Fellowship, Rheumatology, University of Pittsburgh

Board Certification:
Internal Medicine
Rheumatology

Research Interests:
Dr. Manzi's research focus is on the clinical and epidemiological study of systemic lupus erythematosus (SLE). A major emphasis of Dr. Manzi's research is pathogenesis and associated risk factors of premature cardiovascular disease in young women with SLE. Much of the work in this area has been done in collaboration with the Department of Epidemiology at the Graduate School of Public Health (GSPH). Ongoing studies are designed to determine the prevalence of subclinical atherosclerosis using new vascular imaging techniques and the associated traditional cardiovascular risk factors, SLE specific and inflammatory marker variables.

Dr. Manzi, with other collaborators at the GSPH, is examining the association between genetic polymorphisms of the beta 2-glycoprotein 1 gene and the presence of anti-phospholipid antibodies and thrombotic events in SLE.

Other current research endeavors include clinical trials examining the efficacy and safety of new therapeutic agents in SLE, the prevalence of and risk factors associated with osteoporosis, and the risk of malignancy in women with SLE, and the role of hormones in disease activity.

Dr. Manzi is actively participating in the Epidemiology of Women's Health curriculum at the Graduate School of Public Health and is involved in training pre and doctoral candidates in epidemiology and medicine.

Publications:
Dr. Manzi's publications can be reviewed through the National Library of Medicine's publication database by clicking here.